Pharmaceuticals

Thermal analysis is extensively used in pharmaceutical research, production, and quality control. The kind of test depends on whether the studied material is a small molecule or a polymer, an active pharmaceutical ingredient (API) or an excipient, amorphous or crystalline.

Some examples of thermal analysis applications to this area include:
  • Glass transitions
  • Melting points
  • Purity
  • Tg and Tg’ for lyophilized material
  • Detection of amorphous material
  • Polymorphic forms including HyperDSC™
  • Incipient-API interactions
  • Residual solvent by TGA
  • Thermal stability

Tg of a Lyophilized protein by Fast Scanning DSCPharma 1

Purity by DSCPharma 2