Pharmaceuticals

 Pharmaceuticals

Thermal analysis is extensively used in pharmaceutical research, production, and quality control. The kind of test depends on whether the studied material is a small molecule or a polymer, an active pharmaceutical ingredient (API) or an excipient, amorphous or crystalline.

Some examples of thermal analysis applications to this area include:

  • Glass transitions

  • Melting points

  • Purity

  • Tg and Tg’ for lyophilized material

  • Detection of amorphous material

  • Polymorphic forms including HyperDSC™

  • Incipient-API interactions

  • Residual solvent by TGA

  • Thermal stability

Tg of a Lyophilized protein by Fast Scanning DSC

Tg of a Lyophilized protein by Fast Scanning DSC

Tg of a Lyophilized protein by Fast Scanning DSC

Purity by DSC

Purity by DSC